Development of L-Proline-Based Chiral Ionic Liquids for Asymmetric Michael Reaction
نویسندگان
چکیده
Different Chiral Ionic Liquids (CIL) based on L-proline have been developed. Simple and efficient synthetic methodologies are used, allowing preparation in good yields for twelve novel CILs using as a cation or anion combined with suitable counter-ions. A detailed physical chemical characterization of the was performed to evaluate influence counter-ions final properties. The most promissory were tested chiral catalysts IL media asymmetric Michael addition reactions ketones aldehydes nitro-olefins. Similar even better conversions enantioselectivities (ee up 95%) compared original achieved. Additionally, product extraction performance supercritical CO2 processes obtained.
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ژورنال
عنوان ژورنال: Catalysts
سال: 2023
ISSN: ['2073-4344']
DOI: https://doi.org/10.3390/catal13020270